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DiSC Study

DiSC Study 2


Data-informed Stepped Care (DiSC) to Improve Adolescent HIV Outcomes (UH3): A cluster randomized trial on a Data-informed Stepped Care intervention to improve retention among adolescents living with HIV


To develop, pilot, and test a Data informed Stepped Care Intervention in a cluster randomized controlled trial


  • Develop, adapt, pilot, and optimize implementation of data-informed stepped care (DiSC) intervention for ALHIV HIV treatment management
  • Evaluate the effectiveness of the DiSC intervention on ALHIV retention in up to 24 high-volume HIV clinics in Homa bay, Kisumu, and Migori counties in Western Kenya
  • Determine acceptability, feasibility, adaptability, and fidelity of the DiSC intervention
  • Evaluate the effectiveness of the DiSC intervention on ALHIV cascade outcomes (adherence, viral suppression) and adolescent self-efficacy, health service outcomes, and implementation outcomes in high-volume HIV clinics in Homabay, Kisumu, and Migori Counties


Randomized Control Trial


Adolescents and young adults aged 10-24 years enrolled in HIV care, caregivers of HIV-positive adolescents and young adults, policymakers, and stakeholders in adolescent HIV care


Kisumu, Homa bay, and Migori Counties


2 years


National Institute of Health, USA


University of Washington, USA

Local IRB Approval:

Maseno University Ethics Review Committee – MUERC 917/20


Participant recruitment is completed

Current activities: 

Participant follow up

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